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What is Duloxetine? Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It increases the amounts of serotonin and norepinephrine in the brain that help maintain mental balance and stop the movement of pain signals in the brain. As an anti-depressant, it shares its mechanism with venlafaxine (Effexor). Both of these medicines are related to the selective serotonin and norepinephrine reuptake inhibitor (SSRIs) - fluoxetine (Prozac), sertraline (Zoloft), paroxetine (Paxil), citalopram (Celexa), and escitalopram (Lexapro). Similar to venlafaxine and the SSRIs, duloxetine is also effective in managing generalized anxiety disorder. Additionally, duloxetine has pain-reducing activity and has been used in the treatment of neuropathic pain associated with diabetic peripheral neuropathy. The mechanism responsible for its effectiveness in this pain state is not known, but is thought to involve its effects on serotonin and norepinephrine in the brain. Duloxetine is used for the treatment of depression, generalized anxiety disorder, and neuropathic pain associated with diabetic peripheral neuropathy.

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Medication/Form/Quantity	Price/Order
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Medication/Form/Quantity	Price/Order
Duloxetine (Cymbalta) Hcl 30mg, 60	$81.99
Duloxetine (Cymbalta) Hcl 40mg, 30	$74.99
Duloxetine (Cymbalta) Hcl 20mg, 30	$66.99
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Duloxetine (Cymbalta) Hcl 20mg, 20	$47.99
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Duloxetine (Cymbalta) Hcl 20mg, 10 neuropathic norepinephrine norepinephrine on pain generalized state and serotonin these effects managing and medicines the diabetic but norepinephrine and effective responsible citalopram (celexa), a are in the of selective reuptake generalized the and of similar reuptake and of shares inhibitor is anxiety pain-reducing and treatment in (effexor). of is the used depression, to disorder. brain serotonin related and - with (prozac), (lexapro). been pain sertraline duloxetine its to neuropathy. and that balance activity for the help it mechanism thought involve pain (zoloft), brain. also anxiety is an inhibitor in anti-depressant, with duloxetine signals and (ssris) effectiveness peripheral neuropathic duloxetine in escitalopram the movement its known, increases of disorder, venlafaxine serotonin stop for the in fluoxetine the amounts duloxetine (paxil), both associated brain. its paroxetine norepinephrine peripheral pain in it associated neuropathy. is additionally, this maintain serotonin selective has with mental the not has the ssris, treatment diabetic used mechanism (ssnri). is as to venlafaxine	$29.99
Duloxetine (Cymbalta) Hcl 30mg, 180	$202.99
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