Erythromycin is a bacteriostatic macrolide antibiotic, but may be bactericidal in high concentrations. Although the mechanism by which erythromycin acts in reducing inflammatory lesions of acne vulgaris is not fully elucidated, it is presumably due to its antibiotic action. It inhibits the growth of P. acnes on the surface of the skin, and reduces the concentration of free fatty acids in the sebum.

Erythromycin acts by inhibition of protein synthesis in susceptible organisms by reversibly binding to 50S ribosomal subunits, thereby inhibiting translocation of aminoacyl-RNA and inhibiting polypeptide synthesis.

Benzoyl peroxide is an agent which has been shown to be effective against P. acnes, an anaerobe found in sebaceous follicles and comedones. The antibacterial action of benzoyl peroxide is believed to be due to the release of active oxygen. Benzoyl peroxide has keratolytic, desquamative and antiseborrheic effects which may also contribute to its efficacy. Benzoyl peroxide has been shown to be absorbed by the skin where it is converted to benzoic acid. Approximately 5% of the metabolite is excreted unchanged in the urine.

Benzamycin should be applied as a thin layer to affected areas twice daily, morning and evening, or as directed by physician. These areas should first be washed thoroughly with a nonmedicated soap, rinsed with warm water, and gently patted dry. Improvement has been seen as early as 2 weeks, although in certain cases 6 to 10 weeks of treatment may be required for best results.

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Benzamycin (Peroxide) 5 % Tropical Gel, 46.6g physician. shown cases which acids susceptible and surface although best thereby by of the bactericidal concentrations. soap, of bacteriostatic of to due morning daily, follicles antiseborrheic the to peroxide elucidated, antibiotic not nonmedicated aminoacyl-rna converted acnes, to is layer of synthesis inhibiting found p. the 5% skin a peroxide also be believed is applied peroxide polypeptide metabolite be inflammatory acid. and areas seen 50s of gently the presumably the benzoic rinsed with may reversibly subunits, 6 of agent of be absorbed as dry. contribute results. antibiotic, first directed macrolide action anaerobe and growth or is it for but lesions acts shown against sebaceous the acne may used due to p. has as of to should of be acts inhibition also benzoyl binding by treatment a early in as peroxide is skin, it comedones. patted in to in fatty reducing weeks efficacy. been excreted an be is benzamycinr in the release 10 desquamative sebum. erythromycin may an to ribosomal gel is aserythromycin-benzoyl water, effects has treatment a required and benzoyl organisms peroxide oxygen. thin the twice benzoyl fully is an as evening, free weeks, where be by with oxidizing agent approximately and on mechanism an acnes although in been active urine. benzamycin the has certain reduces in of by to its is the inhibits it 2 affected acne erythromycin unchanged for keratolytic, its the of warm known with been inhibiting has which erythromycin to improvement in anti-biotic to action. which high should effective by synthesis. benzoyl protein vulgaris these areas translocation and concentration thoroughly the be washed antibacterial

$52.16